Entire human colonies are disappearing on the fringes of known space in Mass Effect 2. Two years after repelling the Reapers, Commander Shepard must work with Cerberus, a ruthless organization committed to human survival at any cost, to confront the threat.
Shepard recruits a team that includes trusted allies and new fighters. Alongside armed combat, players navigate crew disagreements and intergalactic diplomacy, with prompt-based actions allowing them to interrupt conversations and potentially alter outcomes. An inventory system lets Shepard equip weapons quickly, while regenerating health reduces the need to search for restorative items.
